Behavioral and biochemical changes in Wister albino rats exposed to different brands of vulcanizer solutions

Volatile solvents are liquids that vapourize at room temperature and found in a multitude of inexpensive, easily available products used for common household industrial purposes. There is an increased abuse inhalants among the youths Nigeria purpose mind-alteration or getting high. Vulcanizer solutions one widely lack proper labelling hence there may be adulteration these substances which could also dangerous to health sniffers. The objective this research was subject wistar albino rats different brands vulcanizer investigate possible effects have on social behaviour as well significant changes concentrations some liver function enzymes. Commercial assay kit from Randox Laboratories Ltd determination enzymes interest. study only alanine aminotransferase (ALT) significantly (P ˂ 0.05) behaviours exposition miliki diamond (MD) were observed. Serum ALT, AST ALP levels been reported increase than normal various hepatocellular damages such necrosis, hepatitis, etc. However, ALT more specific detection hepatotoxicity, therefore its increase, when other do not indicates (specifically MD) contribute enormously certain diseases. enzyme concentration due chemicals constituents (such benzene, toluene, ethyl, etc) solutions. Therefore, sniffers highly susceptible diseases organs, prevalence being recently reported.